Dr. Sudad Saman graduated with a master’s degree in bioinformatics from New York University. He continued his studies in a doctoral program in biomedical engineering at the University of Massachusetts with a research focus on Alzheimer’s disease, ultimately earning his Ph.D.
Dr. Saman has published many peer reviewed publications on the study of Alzheimer’s disease with respect to the role of exosomes and the release of tau protein, one of the main markers that detects Alzheimer’s disease. Dr. Saman collaborates with scientists at Boston University and the University of Massachusetts who work on traumatic brain injuries and the detection of tau protein in bodily fluids such as CSF (cerebrospinal fluid), blood, and saliva. His current research involves the identification of microRNA in different body fluids that can function as early detection of Alzheimer’s disease. Similarly, tau is being studied as a marker for the detection of prostate cancer. Dr. Saman’s research involves many applications in biology including: molecular biology, proteomics, and bioinformatics.
Proteins recruited to exosomes by tau overexpression implicate novel cellular mechanisms linking tau secretion with Alzheimer’s Disease, Sudad Saman , Norman C.Y. Lee, Itoro Inoyo, Jun Jin1, Zhihan Li, Thomas Doyle, Ann C. McKeeand Garth F. Hall, Journal of Alzheimer’s disease: JAD (Impact Factor: 4.17). 04/2014; DOI: 10.3233/JAD- 132135.
Death or secretion? – The demise of a plausible assumption about CSF-tau in Alzheimer’s Disease? Garth F. Hall, Sudad Saman, (2012), Communicative and Integrative Biology, Volume 5, Issue 6 November/December 2012. DOI: 10.4161/cib.21437.
Lee E. Goldstein,Andrew M. Fisher, Chad A. Tagge, Xiao-Lei Zhang, Libor Velisek, John A. Sullivan, Chirag Upreti, Jonathan M. Krach, Maria Ericsson, Mark W. Wojnarowicz, Cezar J. Goletiani, Giorgi M. Maglakelidze, Noel Casey, Juliet A. Moncaster, Olga Minaeva, Robert D. Moir, Christopher J. Nowinski, Robert A. Stern, K. Blusztajn, Benjamin L. Sudad Saman, Garth F. Hall, William C. Moss, Robin O. Cleveland, Rudolph E. Tanzi7,Patric K. Stanton5 and Ann C. McKee2. (2012) “Chronic Traumatic Encephalopathy in Blast-Veterans and a Blast Neurotrauma Mouse Model”, Sci Transl Med 16 May 2012. DOI: 10.1126/scitranslmed.3003716.
Sudad Saman et al. (2011), Tau is secreted via exosomes in tauopathy models and resembles CSF-tau in AD – Journal of Medicine.